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A Biosynthetic Matrix (BSM) Technology


PermeaDerm® Biosynthetic Wound Matrix

Revolutionizing wound management for chronic wounds & burns

 

A Biosynthetic Matrix (BSM) Technology

Epidermal Analogue

  • Enabling oxygen, carbon dioxide and exudate to diffuse to/from the wound as needed

    Variable slits: Enhance fluid management

    Transparent: Visual

    Highly flexible: Compliant with anatomy

    Hydrophilic: Sustains optimal healing environment

 

Dermal Analogue

  • Biomimetic fiber 3D micro-support system: Embedded in silicone membrane to stabilize structure throughout the healing process

  • Biological components are added to coating to increase hydrophilic and hygroscopic properties enabling a moist, but not wet environment conducive to healing

  • Structure permits cell migration. Dermis layer enlarges contact area and helps stimulate proliferation and ADHERENCE of cells

Enhanced Clinical Outcome

Improved healing environment 

Effective wound closure

Diminished pain

Lower scar formation*

* Clinical Study Data on File

Innovative Product PermeaDerm®

Ultrathin

Transparent

Excellent physical attributes (flexibility, compliance, strength, stretchability, stability)

Easy to secure

Excellent shelf life

Improved User Experience

Effective adherence

Proliferation acceleration

Wound barrier & nerve protection

Single application (superficial wounds)

Visualization of wound healing


Mode of Action - R.A.S.E

Reconstruction of Skin Barrier & ECM

Prevents contamination and protects inner vessels & nerves. Monitors and maintains moisture balance. Provides extracellular matrix environment.

Primary Adherence

Analogue ECM (bio-components) achieved within 5hrs. allowing interaction with fibrin to form a clot within the micro-support system.

Secondary Adherence

3D structure achieved within 72 hours facilitating cell migration, proliferation, and ingrowth.

Epithelialization

Re-epithelialization was achieved, and the wound healed.

 

Indications

PermeaDerm® Gloves

PermeaDerm®

Partial thickness burns wounds and other partial thickness wounds

Donor sites

coverage of meshed autograft

  • Pressure sores

    Venous ulcers

    Diabetic ulcers

    Vascular ulcers

  • Post-Mohs

    Post-laser surgery

    Podiatric

    Wound dehiscence

  • Abrasions

    Lacerations

    Skin tears

    Draining wounds

Debrided partial thickness hand burns

Case 1: Deep Partial-thickness Burn (Lower Extremity)

Day 0

Day 8

Day 15, healed

6 mos

Case 2: Deep Partial-thickness Hand Burn

Day 0

Day 0, applicaiton

Week 1, healed

Week 3

Week 7

 

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